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Abstract #0433

Dephased MRI separating magnetic susceptibility effects from partial volume effects

Bakker C, Vincken K, Seppenwoolde J
University Medical Center Utrecht

By applying dephasing gradients, called dephased MRI, local magnetic field inhomogeneities (e.g. created by magnetically labeled cells) can be selectively visualized with positive contrast. Next to that, dephased MRI improves visualization of sub-voxel structures by partial-volume effects. What remained unclear so far was the actual contribution of partial volume (PV) and magnetic susceptibility (X) effects in creating the dephased MRI signal. In this work, we present the theory and supportive phantom experiments of two strategies to separate PV and X-effects during application of dephased MRI. The results show that both strategies are successful in eliminating PV effects.