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Abstract #0502

Determination of the ischemic threshold for cell death in acute stroke

Shin W, Rohany M, Cashen T, Carroll T, Walker M, Shaibani A, Sawlani R
Northwestern University

The Bookend method has been presented with water exchange effects correctionfor quantitative cerebral blood flow (qCBF) measurement. Acute strokepatients were scanned with the Bookend protocol, and qCBF maps wereobtained. The diagnostic accuracy for ischemic threshold was determinedusing an ROC analysis, and the ischemic threshold values were estimated in white matter and gray matter, respectively.