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Abstract #0581

Proton Chemical Shift Imaging for Characterization of Heterogeneous Human Breast Tumors

Baik H, Su M, Yu H, Nalcioglu O, Chen J
University of California-Irvine

The chemical-shift imaging (CSI) is a useful technique for analyzing the regional heterogeneity of tumor metabolites. We applied high-resolution 2D-CSI technique to measure the spatial heterogeneity of choline-containing compounds (Cho) in malignant and benign breast lesions and demonstrated the feasibility of this technique for characterizing breast tumors within an acceptable scan time. Therefore, we conclude that the use of CSI technique for a clinical 1.5T study might be of value for further characterization of DCE-MRI enhanced lesions to improve specificity.