Abstract #0741

Connelly A, Groeschel S, Vollmer B

In order to quantify and localise morphometric changes during brain development structural high resolution MRI data of 159 subjects from birth to 30 years of age were analysed using voxel-based morphometry. The total volumes of both grey and white matter increase non-linearly over this age range. Relative to brain size, overall grey matter volume decreases non-linearly over this age range, whereas overall relative white matter volume increases. Regression analyses with age as a covariate have been performed during childhood, adolescence, and young adulthood, revealing regional changes in tissue concentration and volume both in grey and white matter structures.