SSFP-based spectral editing for imaging of 19F contrast agents
Keupp J, Schaeffter T
Philips Research Laboratories
Typical shortcomings of non-proton MRI can be addressed by steady-state free precession (SSFP) methods, which offer a high signal level, short imaging time and spectral selective properties. Imaging of 19F contrast agents can benefit particularly from SSFP because of the complex multi-line spectra with large chemical shift (CS) range. The CS artifact of perfluoro-octyl-bromide can be reduced to two main components using the SSFP frequency response. Weak components, which cause image blurring, are eliminated. The remaining components can be combined in a single image after Dixon-type CS compensation. 19F phantom experiments were performed on a clinical 3T MR scanner.