The effects of magnetic field inhomogeneity on FLASH-based T1 measurements
Mintzopoulos D, Inati S
Harvard Medical School, Harvard Medical School
Multiple FLASH experiments with different flip angles and/or repetition times have been proposed as an efficient, fast, low SAR method for measuring T1 in vivo. Using analytical arguments and numerical experiments we show that the simultaneous estimation of the physical parameters T1, spindensity and B1 from finite-TR FLASH data is ill-posed, irrespective of the number of flip angles and TRs, short or long.