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Abstract #0959

Normal Regional T1 and T2 Relaxation Times of the Brain at 3T

Lee C, Baker E, Thomasson D

The recent trend is to apply quantitative measurements to a variety of brain diseases, since quantifiable abnormalities are detectable in areas of the brain that have normal visual appearance on T1- and T2-weighted images. Quantitative measurements have the potential to be used for establishing objective diagnostic criteria. They also can detect subtle changes over time, useful for monitoring progression of disease or response to treatment. As a reference for future studies of disease, it is helpful to have a thorough description of what is normal. The purpose of this study is to establish reference values and estimate normal variance. We have produced an extensive table of normal values for different regions of the brain, covering more regions with more subjects than previous reports.