Abstract #1036

Fieremans E, Lemahieu I, D'Asseler Y, De Deene Y, Delputte S, Van de Walle R, Achten R

The main application of diffusion tensor imaging (DTI) is to study the white matter geometry in vivo. To validate this technique, we have proposed a flexible hardware phantom by using parallel fibers of woven strands tightly held together by a shrinking tube. In this abstract, the short- and long- time diffusion behaviour of extra cellular diffusion between fibers is modelled by Monte Carlo simulations and experimentally evaluated. The results show that the packing density and the fiber diamter are the most effecting parameters in the phantom design for DTI.