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Abstract #1074

Diffusion Time Dependence of DTI Measurements

Sun S, Song S
Washington University

The effects of restrictions on diffusion measurements are investigated by performing diffusion tensor imaging (DTI) with short and long diffusion time on fixed mouse brain. Both constant b and constant q value approaches were employed. Each line of k-space data was acquired in an interleaved fashion for collecting short and long diffusion time DTI data to eliminate the inter-measurement variation. The results suggest that ADC decreased with increasing diffusion time whether constant q or constant b value was maintained. A more significant ADC reduction was observed in constant q value approach.