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Abstract #1084

Tract Probability Map in Stereotaxic Spaces and Analysis of Asymmetry

Hua K, Wakana S, Zhang J, Jiang H, van Zijl P, Mori S
Johns Hopkins University

Three-dimensional tractography is known to be sensitive to noise, partial volume effects, and complex axonal structures. In this paper, we used a probabilistic approach to tackle these issues. Tracking results of 10 prominent white matter tracts from 28 normal subjects were normalized into common templates and probabilistic maps were generated. The quantification results indicated that 4 tracts related to the temporal lobe are larger in the left hemisphere. The probabilistic maps can be used as an atlas of these tracts and to test effects of diseases on sizes of specific white matter tracts.