The effect of cardiac pulsation on fMRI data analysis
Wu W, Wong E
University of California, San Diego
BOLD signal can be modulated by baseline perfusion that can change with physiological condition and cardiac pulsation. We acquired functional data in synchrony with different cardiac phases and made a comparison with current method that analyzes data over multiple perfusion status. Compatible spatial specificity was found in ASL and BOLD data as images were acquired at different or mixed cardiac phases. Smaller BOLD signal change and larger post stimulus undershoot were found at high baseline perfusion. Gated fMRI has higher effective temporal resolution and can be used for detecting finer hemodynamics.