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Abstract #1116

fMRI During Overt Production of Alternating Elemental English Sounds

Hyde J, Roopchansingh V, Soltysik D
Medical College of Wisconsin

An 8-cycle block trial, where each cycle consists of rapid alternation between two sounds spoken overtly for 14 s followed by 14 s rest, gives rise to intense fMRI signals at 3T using 2 2 2 mm voxels. Motion-induced susceptibility artifacts tend to be at the repetition frequency of the two sounds, which is much higher than the repetition frequency of the task cycle, resulting in a minimal number of false positives. It is concluded that this new paradigm will be useful in fMRI studies of the neurophysiology of sound production.