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Abstract #1293

OPTIMAL BREATHING PROTOCOL FOR DYNAMIC CONTRAST ENHANCED MRI OF SOLITARY PULMONARY NODULE AT 3T

Parker J, Lenkinski R, Hatabu H, DeCamp M, Coute D, Kubo T, Ashiku S, Takahashi M, Kino A
Beth Israel Deaconess Medical Center

The purpose of this study was to evaluate optimal breath instructions that provide less lung parenchyma movement, which can target small lung lesions during dynamic contrast-enhanced MRI scans. Our preliminary results indicate that dynamic contrasted-enhanced MRI of pulmonary nodule is feasible when a shallow breathing protocol is adopted. MR perfusion study of solitary pulmonary nodule using 3T MR system with high spatial and temporal resolution may provide a secondary characterizing method to distinguish benign from malignant nodules with minimal associated risks, thereby avoiding unnecessary intervention for benign lung nodules and associated mortality /morbidity.