Abstract #1322

Conradi M, Woods J, Gierada D, Bartel S, Haywood S

A computer simulation of diffusion within a regular symmetric dichotomous branching model of human lungs has shown the long-range effective diffusivity to be roughly 20 times smaller than what has previously been measured in healthy lungs. Collateral ventilation pathways, which were not implemented in the simulation, may help explain this discrepancy. The simulations and measurements on a healthy volunteer at two different lung volumes preliminarily suggest the role of collateral pathways in long-range diffusion.