Improvements in R2* Mapping During In Vivo Cryoablation
Daniel B, Pauly K, Lu A
Tissue R2* has been shown to be a promising MR parameter for temperature mapping during cryoablation of prostate cancer. However, mapping of R2* in vivo requires ultra-short echo times (TEs) and has been sensitive to eddy currents. In this work a multiple-echo PR readout was used following a half-RF excitation to reduce TE to 100 ms, and eddy currents are carefully measured and compensated. In vivo R2* maps with improved quality have been obtained in the canine prostate throughout the cryoablation. The proposed technique has been shown to be a very promising approach for temperature monitoring during cryosurgery.