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Abstract #1530

Intercompartmental Water Exchange Effects in DCE MRI

Li X, Rooney W, Springer C
Oregon Health & Science University

In Dynamic Contrast Enhanced (DCE) MRI results, the relative importance of the major equilibrium water exchange systems [transendothelial (te), and transcytolemmal (tc)] depends principally on the magnitude of the pseudo first-order rate constant for contrast reagent (CR) extravasation, Ktrans. Here, simulations are used to clearly show this.