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Abstract #1554

Relationship of Temporal Lobe Volume to Neuropsychological Test Performance in Healthy Children and Adolescents

Wells C, Mahone E, Matson M, Kates W, Hay T, Horska A
Johns Hopkins University School of Medicine

The present study examined the relationship between temporal lobe volumes and performance on neuropsychological tests hypothesized to measure either left (Peabody Picture Vocabulary Test-III/PPVT-III) or right (Beery Visual Perception) temporal lobe functioning in a sample of 37 healthy children. After controlling for total cranial gray matter volume, left temporal (but not left frontal) gray matter volume significantly predicted PPVT-III scores. Right temporal (but not right frontal) gray matter volume significantly predicted Visual Perception scores. This convergent and discriminant evidence supports the use of volumetric MRI in healthy children for establishing the ecological validity of neuropsychological tests.