Cellular imaging of rat aortic endothelial cell monolayer using a 3T whole body scanner
Seifert F, Schmitt-Knosalla I, Seifert M
The aim of this study is to develop methods for an MR based monitoring of the monolayer of endothelial cells seeded onto the luminal side of a vascular graft to get more information about their fate under in vivo conditions. Isolated rat aortic endothelial cells were labelled with small iron oxide particles (VSOP). Seeded vascular grafts were transplanted in a rat interposition model into the region of the abdominal aorta. All measurements with aortic grafts in vitro and in vivo were performed on a 3T whole body scanner.