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Abstract #2103

Extensive T2* Heterogeneity in White Matter Studied by High Resolution MRI at 7T

Koretsky A, van Gelderen P, Li T, Duyn J, Talagala L, Merkle H

High resolution T2*mapping in the human brain were performed at 7T. Surprisingly there was significant heterogeneity in white matter contrast that was not attributed to large veins. This contrast followed major white matter fiber bundles and should enable sensitive detection of changes in white matters. Advantages of the GRE sequence used include the unique contrast mechanisms sensitive to tissue microscopic susceptibility, fidelity against physiological motion artifacts, and relative insensitivity to B1 inhomogeniety