MRI evidence of resting state connectivity in rodent brain
Williams K, Peltier S, LaConte S, Keilholz S
Georgia Institute of Technology, Emory University
This work looks for evidence of resting state connectivity in the rat brain similar to that which has previously been observed in humans. Six rats were imaged on a Bruker 11.7 T scanner using a single-shot gradient-echo EPI sequence to acquire T2*-weighted MR images. Power spectra obtained from SI show structure in low frequencies that is not present in spectra from the sagittal sinus or outside the brain, suggesting that resting state fluctuations are present in rats. Correlation maps created using a seed in SI demonstrate increased correlation in the cortex compared to subcortical structures.