MRI estimation of donor liver graft steatosis prior to orthotopic liver transplantation: Feasibility and evaluation of possible RF heating effects
Hollingsworth K, Lomas D, Maguire S, Graves M
University of Cambridge
Steatosis of donor liver grafts adversely affects the outcome of human orthotopic liver transplantation and is currently assessed subjectively by the transplanting surgeon. As a preliminary to using an established rapid MRI method for quantifying donor liver graft steatosis this work used a porcine liver phantom to assess the feasibility of examining an undisturbed sterile packaged cooled liver graft and any expected or observed heating effects of the MR protocol employed. The protocol allowed rapid quantification of liver fat fraction and no expected or observed increase in graft temperature was demonstrated, making it suitable for use with human liver grafts.