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Abstract #2492

Quantitative Magnetization Transfer Bound Pool Mapping at 3T

Newbould R, Bammer R, Liu C, Ropele S
Stanford University

Quantitative magnetization transfer (MT) imaging has been limited at higher fields as most sequences are quite SAR-intensive, and can be hampered by long T1s. Here, a stimulated echo quantitative bound pool fraction (BPF) mapping sequence is presented which has extremely low SAR, and produces high resolution BPF images. The small signal attributable to the MT effect has been magnified by the use of higher field strength, 3.0T. One drawback to the current implementation is sensitivity to ΔB1, which is worse at higher fields, but may be alleviated through alternate RF pulses. Even so, exceptional BPF images with excellent gray/white contrast may be produced.