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Abstract #2548

3He T1 in Mouse Lung estimated from Washout Curve Analysis under Spontaneous Respiration. Use of SF6 Gas at Thermal Equilibrium to evaluate Respiratory Term

Imai H, Inoshita H, Narazaki M, Fujiwara H, Kimura A
Osaka University

We estimated 3He T1 in mouse lung under spontaneous respiration by a novel method, in which SF6 gas at thermal equilibrium was utilized in combination with the hyperpolarized 3He gas in the quantitative washout curve analysis. The estimated 3He T1 value was moderate compared with the value calculated from literature data measured during breath-hold. Thus, 3He T1 is shown to be readily estimated in noninvasive manner.