Abstract #2709

Harris A, Govindaraj M, Frayne R

ADC and FA are used to examine acute ischemic stroke. Here we calculate the minimum detectable difference in white matter (WM) and grey matter (GM) and examine variability for region-of-interest analysis in ADC and FA. The minimum detectable difference for ADC was 0.1610-3 mm2s-1 and 0.2110-3 mm2s-1 in WM and GM, respectively. For FA, the minimum detectable differences were 0.19 and 0.10 in WM and GM, respectively. There was no variability difference between drawing elliptical or free-hand regions of interest. The reliability was substantial within observers; however, there was much lower reliability between observers.