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Abstract #2732

Two Tensor Analysis for White Matter Tractography - Methodological Evaluation

Westin C, Peled S
Brigham and Women's Hospital and Harvard Medical School

Two tensor analysis to resolve crossing tracts in white matter can be performed using standard clinical DTI data when certain geometrical constraints are incorporated. In this work the constrained two-tensor method is critically evaluated using simulations to determine: A) in which cases it is applicable, B) what the associated errors in tract determination are, and C) the optimal data acquisition parameters.