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Abstract #2752

Spatial resolution dependence of DTI tractography in human occipito-callosal region

Kim M, Ronen I, Ugurbil K, Kim D
University of Minnesota

DTI and fiber tracking have been used to measure the fiber structural connectivity in humans in a non-invasive manner. However, low sensitivity is a principal limitation of these methods, causing a large number of possibly missing fiber tracts. Here we studied how the spatial resolution affects the sensitivity of the fiber tracing by rescaling data to five different resolutions. Our data suggest that the spatial resolution can change the degree of the asymmetric cross-callosal connections. We conclude from our study that the spatial resolution of the acquired data will have to be taken into consideration in interpreting DTI data.