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Abstract #2836

Application of Distortion Correction Procedures to Spin-Echo EPI for fMRI Studies in the Temporal Lobe

Embleton K, Parker G, Lambon Ralph M
University of Manchester

Spin-echo EPI was used as the basis for an fMRI experiment to detect activation in regions of temporal lobe where changes in magnetic susceptibility precluded the use of gradient-echo EPI due to intravoxel dephasing. Additionally, different ways of applying a previously described distortion correction using dual-direction kspace traversal were tested. These included acquiring data with both interleaved opposite direction kspace traversal and data with a single direction traversal and a dual traversal pre-scan. Cluster analysis of group data showed significant activation in temporal lobe and other brain regions from a distortion corrected dataset