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Abstract #2908

Longitudinal studies of angiogenesis in hormone dependent Shionogi tumours

Wade T, Kozlowski P
University of British Columbia

Vessel size index (VSI) measurements were performed on 17 mice withsubcutaneous Shionogi tumours. The VSI was tracked as the tumoursprogressed from an androgen dependent state to an androgen independentstate, and no tumour size dependence was found in any of the stages. Apaired t-test on the measurements on the 6 mice that progressed toandrogen independence indicated significant changes in VSI between thestages of tumour progression.