Abstract #2943

Liu Y, Ma J

Phase sensitive inversion recovery images reconstructed from a region growing-based algorithm have an intrinsic ambiguity in the global polarity (GP). Determining GP using the previously proposed net magnetization (NM) or moment of inertia (MI) is found to be dependent on the imaging parameters such as TI, as well as the field strength. In this work, this dependency was removed with a theoretical calculation of the white matter signal polarity. A hybrid scheme employing both NM and MI was shown capable of automatically determining the correct GP of images collected over a wide range of TI and at both 1.5T and 3.0T.