An optimized DENSE acquisition scheme for brain displacement mapping
Boesiger P, Rutz A, Kozerke S, Soellinger M
University and ETH Zurich
Studying pulsatile brain motion caused by cerebral blood flow allows insights into alteration of the dynamics in the cranium in certain brain diseases. We propose a modified DENSE (Displacement Encoded Stimulated Echo) acquisition scheme for 2D cine displacement imaging which allows eliminating phase errors from the spoiling gradients and the EPI read-out train. A 3D phase-unwrap-algorithm was incorporated to permit encoding frequencies up to 10 cycles/mm. With the method proposed 2D displacement data could be acquired over the whole brain in all 3 directions with a spatial resolution of 2x2x4 mm3 and temporal resolution of 25 ms.