Abstract #3219

Wang X, Greenman R, Veves A

In diabetes, functional abnormalities of the foot microvasculature impede the delivery of oxygen to the local tissues resulting in impaired metabolism, which can be measured using phosphorus-31 chemical shift imaging (31P-CSI). However, 31P-CSI suffers from poor spatial and temporal resolution. Phosphorus rapid acquisition with relaxation enhancement (31P-RARE) has been shown to provide higher spatial and temporal resolution and has also been used to assess diabetic foot muscle. The aim of this study was to compare the of the 31P concentrations in the foot muscles of diabetic and normal subjects as measured using 31P-CSI and 31P-RARE.