Effects of Cations and pH on Optimized Assessment of Prostatic Citrate at 3 Tesla
Mulkern R, Takei N, Kaji Y, Sugimura K, Kuroda K, Maeda T
Children's Hospital, Harvard Medical School
Effects of cations and pH on assessment of citrate using PRESS at 3 Tesla were examined in a TE range of 25-300 ms. J-modulated signal intensity curves versus TE of 90-mM citrate solutions with divalent cations shifted markedly with cation concentrations in the order of Ca2+ > Zn2+ > Mg2+. No apparent TE shift was observed for solutions with monovalent cations including Na+ and K+, and for pH values of 6.0-9.0, whereas marked amplitude changes observed. Regardless of the notable TE shift due to divalent cations, peak amplitudes of 130-140 ms were observed for citrate signal of the prostate in each healthy volunteer.