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Abstract #3250

Breath-hold perfusion of hepatic malignancies using dynamic susceptibility contrast-enhanced echo-planar imaging: A preliminary study

weijun p, bin w
cancer hospital

The degree of the signal drop during the first pass (i.e. perfusion phase) is directly proportional to the concentration of contrast agent in the blood. A graph of transient signal drop versus time can be used to compute hemodynamic blood volume map reflecting the microvascularity of the tissue and detecting hemodynamic blood changes after treatment such as transcatheter arterial chemoembolization(TACE) and anti-angiogensis therapy. In this pilot work, we investigate the feasibility of doing this procedure in abdominal regions, and focus on the quantitative analysis of time-intensity curves as well as the enhancement patterns with further assessment of effectiveness after treatment