Abstract #3268

Yund E, Kang X, Herron T, Woods D

A new method, anatomical space analysis (ASA), was proposed, whereby low-resolution functional images are co-registered and resampled directly into high-resolution anatomical space with subsequent data processing performed in high-resolution space. Compared with the widely used functional space analysis (FSA) method, one major advantage of ASA is that minor head movements which are generally assumed to reduce spatial resolution can actually increase spatial resolution by providing multiple samples of the relationship between functional and anatomical space. Both simulations and analyses of real fMRI data show that ASA improves the precision, objectivity and reproducibility of functional brain image mapping.