Abstract #3424

Hendrikse J, Petersen E, Van Laar P, Golay X

Numerous studies have tried to establish the vulnerability of cerebral borderzone areas to a drop in perfusion pressure. Thusfar no imaging method can depict the exact location of the cerebral borderzone regions. Here we show that it is possible to visualize the borderzone regions between the distal branches of the cerebral arteries with arterial spin labeling MRI based on an increase in arterial blood transit time of 0.430.04 s towards these areas. Unexpectedly, a 379% reduction in arterial blood volume and 207% reduction in cerebral blood flow was observed in the cortical borderzone areas.