MR Detection of Tumor Cells Labeled with USPIO using DOPS Liposomes
Kaimal V, Schmithorst V, Qi X, Holland S
University of Cincinnati, Cincinnati Children's Hospital Medical Center
Human neuroblastoma cells were labeled in vitro with dextran coated USPIO nanoparticles delivered using DOPS liposomes. Increased USPIO content in the liposomes was achieved using a chemical linking method. The cells were detected using high resolution T2* weighted gradient echo MRI.