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Abstract #0032

Comparison of ASL and PWI Perfusion in Stroke Patients

Esben Thade Petersen1,2, Tchoyoson C.C. Lim2, N Venketasubramanian2, Xavier Golay2,3

1Center of Functionally Integrative Neuroscience, University of Aarhus, Aarhus, Denmark; 2National Neuroscience Institute, Singapore; 3Institute of Neurology, University College London, UK

One obvious problem of ASL in stroke imaging is the limited duration of the label, which makes it arguable whether ASL will have a chance as compared to PWI when it comes to penumbra estimation and subsequent risk-benefit weighting of possible intervention. In this work we show that ASL acquired at multiple time-points provides similar information to PWI in the affected areas. In addition, ASL can probe the existence of collateral perfusion and combined they could potentially be valuable in this risk assessment. However it still remains to future studies of hyperacute stroke to tell whether ASL can prove sufficient.