Abstract #0037

ADC Values in the Corticospinal Tract at the Acute Stage Can Help Predict Stroke Outcome

Charlotte Rosso^1,2, Olivier Colliot², Christine Delmaire³, Romain Valabregue³, Sylvain Baillet², Sophie Crozier¹, Didier Dormont^2,4, Yves Samson¹, Stphane Lehricy^3,4

¹Stroke Center, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France; ²Cognitive neuroscience and Brain Imaging Laboratory, CNRS-UPR 640 LENA, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France; ³Center for NeuroImaging Research, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France; ⁴Department of Neuroradiology, Pitie Salpetriere Hospital, University Pierre and Marie Curie, Paris, France

We used DWI and ADC maps acquired in the first six hours of stroke onset-H6 and the day after-D1 to predict ischemic stroke outcome at three months in 76 patients. Normalized ADC maps were analyzed for differences between patients with good and poor outcome. ADC values in the corticospinal tract were measured in both groups and used to classify patients according to outcome. ADC values were lower in the CST of patients with poor than patients with good outcomes at both examinations (p<0.05). ADC values in the damaged CST predicted outcome with 65% accuracy at H6 and 71% at D1.