Abstract #0039

Oxygen Metabolic Index as a Predictor of Tissue Viability in Acute Ischemic Stroke Patients

Hongyu An¹, Andria L. Ford², Katie Vo³, William J. Powers⁴, Jin-Moo Lee², Weili Lin¹

¹Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; ²Neurology, Washington University in St. Louis, St. Louis, MO, USA; ³Radiology, Washington University in St. Louis, St. Louis, MO, USA; ⁴Neurology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

We have utilized MR_OMI to assess the cerebral oxygen metabolic activity sequentially (<3.5 hours and at 6 hours) in hyper-acute stroke patients. By using the reperfusion and final infarct status, tissue with different outcomes (dead or alive) were examined in regions either with or without reperfusion. We found that dead tissue had much lower MR_OMI values than alive tissue independent of reperfusion status, suggesting that MR_OMI is capable of predicting tissue outcome in hyper-acute ischemic stroke.