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Abstract #0042

Investigating the Sources of Phase Contrast: Iron Oxide Nanoparticle Study to Exclude Deoxyhemoglobin as a Major Source for the Gray/white Matter Phase Contrast

Jongho Lee1, Yoshiyuki Hirano, Masaki Fukunaga1, Afonso Silva, Jeff H. Duyn1

1Advanced MRI/LFMI/NINDS, National Institute of Health, Bethesda, MD, USA

An intravascular contrast agent (iron oxide nanoparticle) was used to investigate the sources of phase contrast. The result indicates that deoxy-hemoglobin is not a major source for the white and gray matter contrast.