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Abstract #0049

Three-Dimensional Segmentation of the Internal Structures of the Human Hippocampus at 7 Tesla

Marie Chupin1, Stephane Lehericy2,3, Olivier Colliot1, Malgorzata Marjanska4, Ute Goerke4, Kamil Ugurbil4, Pierre-Francois Van de Moortele4

1CNRS UPR 640 - LENA, University Pierre and Marie Curie - Paris 6, Paris, France; 2Center for NeuroImaging Research, University Pierre and Marie Curie - Paris 6, Paris, France; 3Neuroradiology, Inserm U610, Pitie-Salpetriere Hospital, Paris, France; 4Center for Magnetic Resonance Research and Department of radiology, University of Minnesota, Minneapolis, MN, USA

In this work, we used 7T whole body to image and segment in three dimension the internal structure of the human hippocampus. Three human volunteers were included. Six subparts of the hippocampus were clearly differentiated including the stratum pyramidale of the cornu ammonis (CA), more precisely the first 3 segments of CA (CA1-3), the hilum of the dentate (corresponding to the dentate proper and CA4), the subiculum, the alveus and the fimbria. Segmentation of the internal structure of the hippocampus at 7T provides new biomarkers that can be used in brain pathologies.