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Abstract #0061

Four-Dimensional Transcatheter Intraarterial Perfusion MRI Monitoring of Chemoembolization for Hepatocellular Carcinoma

Dingxin Wang1, Ron Gaba2, Robert Lewandowski2, Robert Ryu2, Kent Sato2, Mary Mulcahy3,4, Riad Salem2,4, Reed Omary1,4, Andrew Larson1,4

1Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, USA; 2Department of Radiology, Northwestern University, Chicago, IL, USA; 3Department of Medicine, Northwestern University, Chicago, IL, USA; 4Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA

Transcatheter Intra-arterial Perfusion TRIP-MRI, using catheter-directed intraarterial (IA) contrast delivery, offers an objective method to intra-procedurally quantify tumor perfusion changes during TACE. The TRIP-MRI technique has previously been performed with 2D acquisitions in a combined clinical magnetic resonance/DSA unit (termed MR-IR unit) to monitor TACE. In this study, using a clinical MR-IR unit, we tested the hypothesis that 4D TRIP-MRI can be used to measure intra-procedural perfusion changes in liver tumors during TACE.