Abstract #0061

Four-Dimensional Transcatheter Intraarterial Perfusion MRI Monitoring of Chemoembolization for Hepatocellular Carcinoma

Dingxin Wang¹, Ron Gaba², Robert Lewandowski², Robert Ryu², Kent Sato², Mary Mulcahy^3,4, Riad Salem^2,4, Reed Omary^1,4, Andrew Larson^1,4

¹Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, USA; ²Department of Radiology, Northwestern University, Chicago, IL, USA; ³Department of Medicine, Northwestern University, Chicago, IL, USA; ⁴Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA

Transcatheter Intra-arterial Perfusion TRIP-MRI, using catheter-directed intraarterial (IA) contrast delivery, offers an objective method to intra-procedurally quantify tumor perfusion changes during TACE. The TRIP-MRI technique has previously been performed with 2D acquisitions in a combined clinical magnetic resonance/DSA unit (termed MR-IR unit) to monitor TACE. In this study, using a clinical MR-IR unit, we tested the hypothesis that 4D TRIP-MRI can be used to measure intra-procedural perfusion changes in liver tumors during TACE.