Abstract #0198

Glycine as a Biomarker in Brain Tumors

Valeria Righi^1,2, Dionyssios Mintzopoulos^1,2, Ovidiu C. Andronesi², Peter M. Black³, A Aria Tzika^1,2

¹NMR Surgical Laboratory, MGH & Shriners Hospitals, Harvard Medical School, Boston, MA, USA; ²Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA, USA; ³Neurosurgery, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, USA

We employed high-resolution magic angle spinning proton MR spectroscopy (HRMAS H1 MRS) to evaluate glycine as a biomarker for brain tumors. Glycine in combination with myo-inositol was useful for differentiating glioblasoma multiforme from metastatic brain tumors.