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Abstract #0198

Glycine as a Biomarker in Brain Tumors

Valeria Righi1,2, Dionyssios Mintzopoulos1,2, Ovidiu C. Andronesi2, Peter M. Black3, A Aria Tzika1,2

1NMR Surgical Laboratory, MGH & Shriners Hospitals, Harvard Medical School, Boston, MA, USA; 2Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Boston, MA, USA; 3Neurosurgery, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, USA

We employed high-resolution magic angle spinning proton MR spectroscopy (HRMAS H1 MRS) to evaluate glycine as a biomarker for brain tumors. Glycine in combination with myo-inositol was useful for differentiating glioblasoma multiforme from metastatic brain tumors.