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Abstract #0245

Investigation of Tract-Specific Myelin Content Measures from a Population Averaged Myelin Water Fraction Atlas

Sean CL Deoni1

1Centre for Neuroimaging Sciences, London, UK

Here we report on the development of a whole-brain, population-averaged atlas of myelin content derived from in vivo measurements of the myelin water fraction. 14 healthy individuals were imaging using the mcDESPOT multi-component relaxometry technique, non-linearly coregistered to standard space and averaged. From the resulting whole-brain atlas we demonstrate white matter tract-specific measures and consider the future application of such an atlas for identifying disease-related change.