John J. Sheehan1, Hyun Jeong2, Amir Davarpanah3, Cormac Farrelly1, Randall Ramsy1, Sanjiv Shah4, Tim Carroll2, James C. Carr1,3
1Cardiovascular Imaging, Northwestern Memorial Hospital, Chicago, IL, USA; 2Biomedical Engineering, Northwestern University, Chicago, IL, USA; 3Cardiovascular Imaging, Northwestern University, Chicago, IL, USA; 4Cardiology, Northwestern Memorial Hospital, Chicago, IL, USA
Pulmonary arterial and venous transit times were measured by radial sliding window time-resolved MRA to calculate pulmonary blood volumes and correlated with ventricular volumetrics in patients with pulmonary arterial hypertension (PAH). Radial MRA allows high temporal resolution, free breathing MRA with good separation between arterial and venous phases. Intrapulmonary transit times (ITT) were prolonged in patients with PAH. ITT correlated directly with RVEDV/ESV, and inversely with RVEF. Radial MRA allows determination and separation of intrapulmonary transit times that are prolonged, and pulmonary blood volumes, which are raised in pulmonary arterial hypertension.
Keywords