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Abstract #0332

Gradient Offset Independent Adiabatic Pulses for High-Field MR Spectroscopy on Clinical Scanners

Ovidiu Cristian Andronesi1, Saadallah Ramadan2, Eva Maria Ratai1, Dominique Jennings1, Carolyn Mountford2, A. Gregory Sorensen1

1Martinos Center for Biomedical Imaging, Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA; 2Center for Clinical Spectroscopy, Department of Radiology, Brigham & Womens Hospital, Harvard Medical School, Boston, MA, USA

Adiabatic pulses are necessary to mitigate chemical shift artifact and rf inhomogeneity at high-field MRS, but often they need longer durations (≥ 5 ms) and higher rf strengths (> 1 kHz) that limits their application in-vivo. Gradient offset independent adiabatic (GOIA) pulses have been proposed [1] as an elegant solution to reduce these requirements while effectively increasing the excitation bandwidth (> 20 kHz). Despite of the benefits, their use on clinical scanners has not been widespread. Here we report on a new class of GOIA pulses derived from WURST [3] adiabatic pulses that provide accurate localization and increased SNR at 3T and 7T.