Abstract #0337

High Resolution Magnetization Transfer Imaging at 7T

Olivier E. Mougin¹, Ali al-Radaideh¹, Ron Coxon¹, Emma C. Tallantyre², Matthew J. Brookes¹, Nikos Evangelou³, Penny A. Gowland¹

¹Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, Nottinghamshire, UK; ²Departement of Clinical Neurology, Medical School, University of Nottingham, Nottingham, Nottinghamshire, UK; ³School of Medical & Surgical Sciences, University of Nottingham, Nottingham, Nottinghamshire, UK

High resolution (1x1x1mm3) MTR scans have been acquired at 7T using a novel imaging sequence. The MTR contrast has been compared between 7 and 3T, showing a greater grey matter (GM) / white matter (WM) contrast to noise ratio at 7T, providing a good delineation of WM lesions at high resolution with the MTR contrast. The sequence is being used to study white matter changes in MS patients.