George Rachid de Oliveira1, Earl Michael Chester2, Gregory Wilson1,3, Jeffrey H. Maki1,4
1Radiology, University of Washington, Seattle, WA, USA; 2Medicine, University of Washington, Seattle, WA, USA; 3Radiology, Philips Healthcare, Cleveland, OH; 4Radiology, Puget Sound VA Health Care System, Seattle, WA, USA
The objective was to compare qualitative and quantitative peripheral MRA (pMRA) image quality with different dose high vs. conventional relaxivity contrast agents (HRCA vs. CRCA). SNR and timing optimized 3 station pMRA was performed using similar doses (~0.2 mmol/kg) of HRCA vs. CRCA, as well as a smaller dose (~0.1 mmol/kg) of HRCA. No statistically significant qualitative or quantitative differences were observed between same dose HRCA and CRCA. Furthermore, no differences were observed between 0.2 and 0.1 mmol/kg dosing for HRCA, suggesting low dose HRCA is equivalent to high dose CRCA, and increasing HRCA dose has little benefit for pMRA.