Wolfgang Bogner1,2, Stephan Gruber1,2, Katja Pinker1,2, Gnther Grabner1,2, Andreas Stadlbauer3, Ewald Moser2, Thomas Helbich1, Siegfried Trattnig1,2
1Department of Radiology, Medical University Vienna, Vienna, Austria; 2MR Center of Excellence, Medical University Vienna, Vienna, Austria; 3Landesklinikum St.Plten, St.Plten, Austria
Seventy-four patients suspect for breast cancer were examined on a 3T MR system with an additional DWI protocol. The impact of different diffusion schemes on diagnostically relevant parameters such as CNR and ADC precision/accuracy was investigated. The influence of perfusion and compartment effects on the ADC were studied in the breast. The diagnostic accuracy of an optimized diffusion scheme were determined. The application of such an optimized DWI protocol at 3T provided a diagnostic sensitivity of 96% and specificity of 94% in our patient group of 69 women.