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Abstract #0637

In Vivo MRS Monitor Delayed Neurodegeneration in Experimental Spinal Cord Injury

Junchao Qian1, Juan Herrera1, Ponnada Narayana1

1Diagnostic and Interventional Imaging, University of Texas at Houston, Houston, TX, USA

In vivo proton MRS studies were performed in injured spinal cord at two weeks post-injury. Spectra were acquired at the epicenter, rostral and caudal to the site of injury. A reduction in the NAA levels was observed at all the three segments. This study demonstrates delayed neurodegeneration away from the epicenter of injury.